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Feeding Angptl4(−/−) mice trans fat promotes foam cell formation in mesenteric lymph nodes without leading to ascites

Angiopoietin-like 4 (ANGPTL4) regulates plasma triglyceride levels by inhibiting LPL. Inactivation of ANGPTL4 decreases plasma triglycerides and reduces the risk of coronary artery disease. Unfortunately, targeting ANGPTL4 for the therapeutic management of dyslipidemia and atherosclerosis is hampere...

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Podrobná bibliografie
Vydáno v:J Lipid Res
Hlavní autoři: Oteng, Antwi-Boasiako, Bhattacharya, Asmita, Brodesser, Susanne, Qi, Ling, Tan, Nguan Soon, Kersten, Sander
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454507/
https://ncbi.nlm.nih.gov/pubmed/28412693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M074278
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