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Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation

Mitophagy is an important quality-control mechanism in eukaryotic cells, and defects in mitophagy correlate with aging phenomena and neurodegenerative disorders. It is known that different mitochondrial matrix proteins undergo mitophagy with very different rates but, to date, the mechanism underlyin...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Kolitsida, Panagiota, Zhou, Jianwen, Rackiewicz, Michal, Nolic, Vladimir, Dengjel, Jörn, Abeliovich, Hagai
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789754/
https://ncbi.nlm.nih.gov/pubmed/31548421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901759116
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