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Mitochondrial mitophagic mechanisms of myocardial matrix metabolism and remodelling

High levels of homocysteine (Hcy), known as hyperhomocysteinmia (HHcy), are correlated with an increase in extracellular matrix remodelling (ECM) via the matrix metalloproteinases (MMPs) and plasminogen/plasmin system. This results in an increase deposition of collagen that leads to endothelial-myoc...

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Detalhes bibliográficos
Main Authors: Vacek, Thomas P., Vacek, Jonathan C., Tyagi, Suresh C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269507/
https://ncbi.nlm.nih.gov/pubmed/22181043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/13813455.2011.635660
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