The central role of vascular extracellular matrix and basement membrane remodeling in metabolic syndrome and type 2 diabetes: the matrix preloaded

<p>Abstract</p> <p>The vascular endothelial basement membrane and extra cellular matrix is a compilation of different macromolecules organized by physical entanglements, opposing ionic charges, chemical covalent bonding, and cross-linking into a biomechanically active polymer. Thes...

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Bibliographic Details
Main Authors: Tyagi Suresh C, Sowers James R, Hayden Melvin R
Format: Artigo
Language:Inglês
Published: BMC 2005-06-01
Series:Cardiovascular Diabetology
Subjects:
Atherosclerosis
Collagen
elastin
proteoglycan
structural glycoprotein
Integrin
oxidative stress
redox stress
MMP
TIMP
remodeling
Online Access:http://www.cardiab.com/content/4/1/9
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