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Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation

Mitophagy is an important quality-control mechanism in eukaryotic cells, and defects in mitophagy correlate with aging phenomena and neurodegenerative disorders. It is known that different mitochondrial matrix proteins undergo mitophagy with very different rates but, to date, the mechanism underlyin...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Kolitsida, Panagiota, Zhou, Jianwen, Rackiewicz, Michal, Nolic, Vladimir, Dengjel, Jörn, Abeliovich, Hagai
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789754/
https://ncbi.nlm.nih.gov/pubmed/31548421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901759116
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