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Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation

Mitophagy is an important quality-control mechanism in eukaryotic cells, and defects in mitophagy correlate with aging phenomena and neurodegenerative disorders. It is known that different mitochondrial matrix proteins undergo mitophagy with very different rates but, to date, the mechanism underlyin...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kolitsida, Panagiota, Zhou, Jianwen, Rackiewicz, Michal, Nolic, Vladimir, Dengjel, Jörn, Abeliovich, Hagai
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789754/
https://ncbi.nlm.nih.gov/pubmed/31548421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901759116
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