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Phosphonic Acid Analogues of Phenylglycine as Inhibitors of Aminopeptidases: Comparison of Porcine Aminopeptidase N, Bovine Leucine Aminopeptidase, Tomato Acidic Leucine Aminopeptidase and Aminopeptidase from Barley Seeds

The inhibitory activity of 14 racemic phosphonic acid analogs of phenylglycine, substituted in aromatic rings, towards porcine aminopeptidase N (pAPN) and barley seed aminopeptidase was determined experimentally. The obtained patterns of the inhibitory activity against the two enzymes were similar....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pharmaceuticals (Basel)
Hauptverfasser: Wanat, Weronika, Talma, Michał, Pawełczak, Małgorzata, Kafarski, Paweł
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789573/
https://ncbi.nlm.nih.gov/pubmed/31533309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph12030139
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