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HFE Related Hemochromatosis: Uncovering the Inextricable Link between Iron Homeostasis and the Immunological System

The HFE gene (OMIM 235200), most commonly associated with the genetic iron overload disorder Hemochromatosis, was identified by Feder et al. in 1996, as a major histocompatibilty complex (MHC) class I like gene, first designated human leukocyte antigen-H (HLA-H). This discovery was thus accomplished...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pharmaceuticals (Basel)
Hauptverfasser: Porto, Graça, Cruz, Eugénia, Teles, Maria José, de Sousa, Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789554/
https://ncbi.nlm.nih.gov/pubmed/31443397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph12030122
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