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Iron as a Therapeutic Target in HFE-Related Hemochromatosis: Usual and Novel Aspects
Genetic hemochromatosis is an iron overload disease that is mainly related to the C282Y mutation in the HFE gene. This gene controls the expression of hepcidin, a peptide secreted in plasma by the liver and regulates systemic iron distribution. Homozygous C282Y mutation induces hepcidin deficiency,...
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| Pubblicato in: | Pharmaceuticals (Basel) |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6315470/ https://ncbi.nlm.nih.gov/pubmed/30486249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph11040131 |
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