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Probing the limits of Q-tag bioconjugation of antibodies
Site-selective labelling of antibodies (Abs) can circumvent problems from heterogeneity of conventional conjugation. Here, we evaluate the industrially-applied chemoenzymatic ‘Q-tag’ strategy based on transglutaminase-mediated (TGase) amide-bond formation in the generation of (89)Zr-radiolabelled an...
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| Publicado no: | Chem Commun (Camb) |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6788405/ https://ncbi.nlm.nih.gov/pubmed/31479092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9cc02303h |
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