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(111)In-BnDTPA-F3: an Auger electron-emitting radiotherapeutic agent that targets nucleolin

INTRODUCTION: The F3 peptide (KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK), a fragment of the human high mobility group protein 2, binds nucleolin. Nucleolin is expressed in the nuclei of normal cells but is also expressed on the membrane of some cancer cells. The goal was to investigate the use of (111)In-labe...

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Bibliografische gegevens
Hoofdauteurs: Cornelissen, Bart, Waller, Andrew, Target, Carol, Kersemans, Veerle, Smart, Sean, Vallis, Katherine A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298710/
https://ncbi.nlm.nih.gov/pubmed/22348532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-219X-2-9
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