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Probing the Lipid Annular Belt by Gas‐Phase Dissociation of Membrane Proteins in Nanodiscs

Interactions between membrane proteins and lipids are often crucial for structure and function yet difficult to define because of their dynamic and heterogeneous nature. Here, we use mass spectrometry to demonstrate that membrane protein oligomers ejected from nanodiscs in the gas phase retain large...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Marty, Michael T., Hoi, Kin Kuan, Gault, Joseph, Robinson, Carol V.
Médium: Artigo
Jazyk:Inglês
Vydáno: WILEY‐VCH Verlag 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736441/
https://ncbi.nlm.nih.gov/pubmed/26594028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201508289
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