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Probing the Lipid Annular Belt by Gas‐Phase Dissociation of Membrane Proteins in Nanodiscs

Interactions between membrane proteins and lipids are often crucial for structure and function yet difficult to define because of their dynamic and heterogeneous nature. Here, we use mass spectrometry to demonstrate that membrane protein oligomers ejected from nanodiscs in the gas phase retain large...

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Publicado en:Angew Chem Int Ed Engl
Main Authors: Marty, Michael T., Hoi, Kin Kuan, Gault, Joseph, Robinson, Carol V.
Formato: Artigo
Idioma:Inglês
Publicado: WILEY‐VCH Verlag 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736441/
https://ncbi.nlm.nih.gov/pubmed/26594028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201508289
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