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Probing the Lipid Annular Belt by Gas‐Phase Dissociation of Membrane Proteins in Nanodiscs

Interactions between membrane proteins and lipids are often crucial for structure and function yet difficult to define because of their dynamic and heterogeneous nature. Here, we use mass spectrometry to demonstrate that membrane protein oligomers ejected from nanodiscs in the gas phase retain large...

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Dettagli Bibliografici
Pubblicato in:Angew Chem Int Ed Engl
Autori principali: Marty, Michael T., Hoi, Kin Kuan, Gault, Joseph, Robinson, Carol V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: WILEY‐VCH Verlag 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736441/
https://ncbi.nlm.nih.gov/pubmed/26594028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201508289
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