Poly (ADP‐ribose) polymerase inhibition protects against myocardial ischaemia/reperfusion injury via suppressing mitophagy

Myocardial ischaemia/reperfusion (I/R) injury attenuates the beneficial effects of reperfusion therapy. Poly(ADP‐ribose) polymerase (PARP) is overactivated during myocardial I/R injury. Mitophagy plays a critical role in the development of myocardial I/R injury. However, the effect of PARP activatio...

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Vydáno v:J Cell Mol Med
Hlavní autoři: Cao, Shengchuan, Sun, Yiying, Wang, Wenjun, Wang, Bailu, Zhang, Qun, Pan, Chang, Yuan, Qiuhuan, Xu, Feng, Wei, Shujian, Chen, Yuguo
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787458/
https://ncbi.nlm.nih.gov/pubmed/31379115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14573
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