Activation of Poly(ADP-Ribose) Polymerase by Myocardial Ischemia and Coronary Reperfusion in Human Circulating Leukocytes

Reactive free radical and oxidant production leads to DNA damage during myocardial ischemia/reperfusion. Consequent overactivation of poly(ADP-ribose) polymerase (PARP) promotes cellular energy deficit and necrosis. We hypothesized that PARP is activated in circulating leukocytes in patients with my...

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Detalhes bibliográficos
Main Authors: Tóth-Zsámboki, Emese, Horváth, Eszter, Vargova, Katarina, Pankotai, Eszter, Murthy, Kanneganti, Zsengellér, Zsuzsanna, Bárány, Tamás, Pék, Tamás, Fekete, Katalin, Kiss, Róbert Gábor, Préda, István, Lacza, Zsombor, Gerö, Domokos, Szabó, Csaba
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1770007/
https://ncbi.nlm.nih.gov/pubmed/17225870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/2006-00055.Toth-Zsamboki
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