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Treatment with insulin inhibits poly(ADP-ribose)polymerase activation in a rat model of endotoxemia
In critically ill patients various conditions may lead to the activation of poly(ADP-ribose) polymerase (PARP). By promoting cellular energetic dysfunction, and by enhancing pro-inflammatory gene expression, PARP activation significantly contributes to the pathogenesis of shock. PARP activation is u...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713048/ https://ncbi.nlm.nih.gov/pubmed/18078960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2007.11.001 |
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