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Poly(ADP-Ribose) Polymerase Inhibition in Acute Lung Injury. A Reemerging Concept
PARP1, the major isoform of a family of ADP-ribosylating enzymes, has been implicated in the regulation of various biological processes including DNA repair, gene transcription, and cell death. The concept that PARP1 becomes activated in acute lung injury (ALI) and that pharmacological inhibition or...
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| Publicado no: | Am J Respir Cell Mol Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Thoracic Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7605157/ https://ncbi.nlm.nih.gov/pubmed/32640172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2020-0188TR |
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