Inhibition of adenosine kinase attenuates myocardial ischaemia/reperfusion injury

Increased adenosine helps limit infarct size in ischaemia/reperfusion‐injured hearts. In cardiomyocytes, 90% of adenosine is catalysed by adenosine kinase (ADK) and ADK inhibition leads to higher concentrations of both intracellular adenosine and extracellular adenosine. However, the role of ADK inh...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Wang, Wenjun, Wang, Bailu, Sun, Shukun, Cao, Shengchuan, Zhai, Xiaoxuan, Zhang, Chuanxin, Zhang, Qun, Yuan, Qiuhuan, Sun, Yi, Xue, Mengyang, Ma, Jingjing, Xu, Feng, Wei, Shujian, Chen, Yuguo
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957171/
https://ncbi.nlm.nih.gov/pubmed/33523568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16328
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