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Zinc supplementation increases protein titer of recombinant CHO cells

In order to study the impact of zinc and copper on the titer levels of mAb and recombinant protein in CHO cells, the IgG-expressing (DP12) and EPO-expressing (SK15) cell lines were cultured in chemically defined media with increasing concentrations of either metal. Supplementation with 25 mg/l in CD...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cytotechnology
Egile Nagusiak: Capella Roca, Berta, Alarcón Miguez, Antonio, Keenan, Joanne, Suda, Srinivas, Barron, Niall, O’Gorman, Donal, Doolan, Padraig, Clynes, Martin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Netherlands 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787129/
https://ncbi.nlm.nih.gov/pubmed/31396753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-019-00334-1
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