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An arginase-based system for selection of transfected CHO cells without the use of toxic chemicals
Polyamines have essential roles in cell proliferation, DNA replication, transcription, and translation processes, with intracellular depletion of putrescine, spermidine, and spermine resulting in cellular growth arrest and eventual death. Serum-free media for CHO-K1 cells require putrescine suppleme...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6901305/ https://ncbi.nlm.nih.gov/pubmed/31666335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011162 |
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