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An arginase-based system for selection of transfected CHO cells without the use of toxic chemicals

Polyamines have essential roles in cell proliferation, DNA replication, transcription, and translation processes, with intracellular depletion of putrescine, spermidine, and spermine resulting in cellular growth arrest and eventual death. Serum-free media for CHO-K1 cells require putrescine suppleme...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Capella Roca, Berta, Lao, Nga, Barron, Niall, Doolan, Padraig, Clynes, Martin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901305/
https://ncbi.nlm.nih.gov/pubmed/31666335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011162
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