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Detection of spacer precursors formed in vivo during primed CRISPR adaptation
Type I CRISPR-Cas loci provide prokaryotes with a nucleic-acid-based adaptive immunity against foreign DNA. Immunity involves adaptation, the integration of ~30-bp DNA fragments, termed prespacers, into the CRISPR array as spacers, and interference, the targeted degradation of DNA containing a proto...
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| Pubblicato in: | Nat Commun |
|---|---|
| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6787059/ https://ncbi.nlm.nih.gov/pubmed/31601800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12417-w |
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