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Spacer-length DNA intermediates are associated with Cas1 in cells undergoing primed CRISPR adaptation
During primed CRISPR adaptation spacers are preferentially selected from DNA recognized by CRISPR interference machinery, which in the case of Type I CRISPR–Cas systems consists of CRISPR RNA (crRNA) bound effector Cascade complex that locates complementary targets, and Cas3 executor nuclease/helica...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389516/ https://ncbi.nlm.nih.gov/pubmed/28204574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx097 |
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