Highly efficient primed spacer acquisition from targets destroyed by the Escherichia coli type I-E CRISPR-Cas interfering complex

Prokaryotic clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR associated (Cas) immunity relies on adaptive acquisition of spacers—short fragments of foreign DNA. For the type I-E CRISPR-Cas system from Escherichia coli, efficient “primed” adaptation requires Cas effector prote...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Semenova, Ekaterina, Savitskaya, Ekaterina, Musharova, Olga, Strotskaya, Alexandra, Vorontsova, Daria, Datsenko, Kirill A., Logacheva, Maria D., Severinov, Konstantin
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941421/
https://ncbi.nlm.nih.gov/pubmed/27325762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602639113
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