4-Methylumbelliferone improves the thermogenic capacity of brown adipose tissue

Therapeutic increase of brown adipose tissue (BAT) thermogenesis is of great interest as BAT activation counteracts obesity and insulin resistance. Hyaluronan (HA) is a glycosaminoglycan, found in the extracellular matrix, which is synthesized by HA synthases (Has1/Has2/Has3) from sugar precursors a...

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Publicado en:Nat Metab
Main Authors: Grandoch, Maria, Flögel, Ulrich, Virtue, Sam, Maier, Julia K., Jelenik, Tomas, Kohlmorgen, Christina, Feldmann, Kathrin, Ostendorf, Yanina, Castañeda, Tamara R., Zhou, Zhou, Yamaguchi, Yu, Nascimento, Emmani B.M., Sunkari, Vivekananda G., Goy, Christine, Kinzig, Martina, Sörgel, Fritz, Bollyky, Paul L., Schrauwen, Patrick, Al-Hasani, Hadi, Roden, Michael, Keipert, Susanne, Vidal-Puig, Antonio, Jastroch, Martin, Haendeler, Judith, Fischer, Jens W.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786893/
https://ncbi.nlm.nih.gov/pubmed/31602424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-019-0055-6
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