4-Methylumbelliferone improves the thermogenic capacity of brown adipose tissue

Therapeutic increase of brown adipose tissue (BAT) thermogenesis is of great interest as BAT activation counteracts obesity and insulin resistance. Hyaluronan (HA) is a glycosaminoglycan, found in the extracellular matrix, which is synthesized by HA synthases (Has1/Has2/Has3) from sugar precursors a...

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Detalhes bibliográficos
Publicado no:Nat Metab
Main Authors: Grandoch, Maria, Flögel, Ulrich, Virtue, Sam, Maier, Julia K., Jelenik, Tomas, Kohlmorgen, Christina, Feldmann, Kathrin, Ostendorf, Yanina, Castañeda, Tamara R., Zhou, Zhou, Yamaguchi, Yu, Nascimento, Emmani B.M., Sunkari, Vivekananda G., Goy, Christine, Kinzig, Martina, Sörgel, Fritz, Bollyky, Paul L., Schrauwen, Patrick, Al-Hasani, Hadi, Roden, Michael, Keipert, Susanne, Vidal-Puig, Antonio, Jastroch, Martin, Haendeler, Judith, Fischer, Jens W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786893/
https://ncbi.nlm.nih.gov/pubmed/31602424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-019-0055-6
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