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Eukaryotic elongation factor-2 kinase regulates the cross-talk between autophagy and pyroptosis in doxorubicin-treated human melanoma cells in vitro

Eukaryotic elongation factor-2 kinase (eEF-2K), a negative regulator of protein synthesis, has been shown to play an important role in modulating autophagy and apoptosis in tumor cells under various stresses. In this study, we investigated the regulatory role of eEF-2K in pyroptosis (a new form of p...

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書目詳細資料
發表在:Acta Pharmacol Sin
Main Authors: Yu, Pian, Wang, Hai-yan, Tian, Min, Li, Ao-xue, Chen, Xi-sha, Wang, Xin-luan, Zhang, Yi, Cheng, Yan
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786479/
https://ncbi.nlm.nih.gov/pubmed/30914761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-019-0222-z
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