The Molecular Mechanism of Eukaryotic Elongation Factor 2 Kinase Activation

Calmodulin (CaM)-dependent eukaryotic elongation factor 2 kinase (eEF-2K) impedes protein synthesis through phosphorylation of eukaryotic elongation factor 2 (eEF-2). It is subject to complex regulation by multiple upstream signaling pathways, through poorly described mechanisms. Precise integration...

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Bibliografski detalji
Glavni autori: Tavares, Clint D. J., Ferguson, Scarlett B., Giles, David H., Wang, Qiantao, Wellmann, Rebecca M., O'Brien, John P., Warthaka, Mangalika, Brodbelt, Jennifer S., Ren, Pengyu, Dalby, Kevin N.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Enzymology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156036/
https://ncbi.nlm.nih.gov/pubmed/25012662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.577148
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