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Eukaryotic elongation factor-2 kinase regulates the cross-talk between autophagy and pyroptosis in doxorubicin-treated human melanoma cells in vitro

Eukaryotic elongation factor-2 kinase (eEF-2K), a negative regulator of protein synthesis, has been shown to play an important role in modulating autophagy and apoptosis in tumor cells under various stresses. In this study, we investigated the regulatory role of eEF-2K in pyroptosis (a new form of p...

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Podrobná bibliografie
Vydáno v:Acta Pharmacol Sin
Hlavní autoři: Yu, Pian, Wang, Hai-yan, Tian, Min, Li, Ao-xue, Chen, Xi-sha, Wang, Xin-luan, Zhang, Yi, Cheng, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786479/
https://ncbi.nlm.nih.gov/pubmed/30914761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-019-0222-z
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