High-level protein production in erythroid cells derived from in vivo transduced hematopoietic stem cells

We developed an in vivo hematopoietic stem cell (HSC) transduction approach that involves HSC mobilization from the bone marrow into the peripheral bloodstream and the IV injection of an integrating, helper-dependent adenovirus (HDAd5/35(++)) vector system. HDAd5/35(++) vectors target human CD46, a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood Adv
Egile Nagusiak: Wang, Hongjie, Liu, Zhinan, Li, Chang, Gil, Sucheol, Papayannopoulou, Thalia, Doering, Christopher B., Lieber, André
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2019
Gaiak:
Gene Therapy
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784527/
https://ncbi.nlm.nih.gov/pubmed/31585952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000706
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