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In vivo hematopoietic stem cell transduction

Current hematopoietic stem cell (HSC) gene therapy approaches rely on the collection of patient HSCs, followed by their culture and expansion in vitro, their modification using γ-retrovirus or lentiviral vectors, and their re-infusion into myelo-conditioned patients. While this approach has been suc...

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Detalhes bibliográficos
Publicado no:Hematol Oncol Clin North Am
Main Authors: Richter, Maximilian, Stone, Daniel, Miao, Carol, Humbert, Olivier, Kiem, Hans-Peter, Papayannopoulou, Thalia, Lieber, Andre
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659626/
https://ncbi.nlm.nih.gov/pubmed/28895846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hoc.2017.06.001
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