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In vivo hematopoietic stem cell transduction

Current hematopoietic stem cell (HSC) gene therapy approaches rely on the collection of patient HSCs, followed by their culture and expansion in vitro, their modification using γ-retrovirus or lentiviral vectors, and their re-infusion into myelo-conditioned patients. While this approach has been suc...

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Библиографические подробности
Опубликовано в: :Hematol Oncol Clin North Am
Главные авторы: Richter, Maximilian, Stone, Daniel, Miao, Carol, Humbert, Olivier, Kiem, Hans-Peter, Papayannopoulou, Thalia, Lieber, Andre
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659626/
https://ncbi.nlm.nih.gov/pubmed/28895846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hoc.2017.06.001
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