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Why maximum tolerated dose?

A long‐established approach to the pharmacological treatment of disease has been to start low and go slow. However, clinicians often prescribe up to maximum tolerated dose (MTD), especially when treating acute and more severe disease, without evidence to show that MTD is more likely to improve outco...

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Bibliografske podrobnosti
izdano v:Br J Clin Pharmacol
Main Authors: Stampfer, Hans G., Gabb, Genevieve M., Dimmitt, Simon B.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783596/
https://ncbi.nlm.nih.gov/pubmed/31219196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14032
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