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The rationale of dose–response curves in selecting cancer drug dosing

Drug development for cancer chemotherapy has an interesting history. A mix of serendipity, animal, cell line, and standard pharmacological principles of dose, dose‐response, dose‐concentration, dose intensity and combination therapies have been used to develop optimal dosing schedules. However in pr...

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Publicat a:Br J Clin Pharmacol
Autors principals: Martin, Jennifer H., Dimmitt, Simon
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783605/
https://ncbi.nlm.nih.gov/pubmed/31077412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13979
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