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Efficacy and toxicity of antihypertensive pharmacotherapy relative to effective dose 50

Antihypertensive drugs have usually been approved at doses near the top of their respective dose–response curves. Efficacy plateaus but adverse drug reactions (ADRs), such as falls, cerebral or renal ischaemia, increase as dose is increased, especially in older patients with comorbidities. ADRs redu...

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Bibliografische gegevens
Gepubliceerd in:Br J Clin Pharmacol
Hoofdauteurs: Dimmitt, Simon B., Stampfer, Hans G., Martin, Jennifer H., Ferner, Robin E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783604/
https://ncbi.nlm.nih.gov/pubmed/31219198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14033
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