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Efficacy and toxicity of antihypertensive pharmacotherapy relative to effective dose 50
Antihypertensive drugs have usually been approved at doses near the top of their respective dose–response curves. Efficacy plateaus but adverse drug reactions (ADRs), such as falls, cerebral or renal ischaemia, increase as dose is increased, especially in older patients with comorbidities. ADRs redu...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6783604/ https://ncbi.nlm.nih.gov/pubmed/31219198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14033 |
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