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Why maximum tolerated dose?

A long‐established approach to the pharmacological treatment of disease has been to start low and go slow. However, clinicians often prescribe up to maximum tolerated dose (MTD), especially when treating acute and more severe disease, without evidence to show that MTD is more likely to improve outco...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Stampfer, Hans G., Gabb, Genevieve M., Dimmitt, Simon B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783596/
https://ncbi.nlm.nih.gov/pubmed/31219196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14032
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