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IL-25 orchestrates activation of Thelper cells via conventional dendritic cells in tissue to exacerbate chronic HDM-induced asthma pathology

House dust mites (HDM) extract is a common trigger of asthma in humans. Chronic exposure to HDM also induces asthma-like pathology in mice. Allergic responses to HDM and other allergens are linked to release of IL-25, IL-33 and TSLP by epithelial cells; these cytokines, especially IL-33, target inna...

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Publicado en:J Immunol
Main Authors: Claudio, Estefania, Wang, Hongshan, Kamenyeva, Olena, Tang, Wanhu, Ha, Hye-lin, Siebenlist, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783368/
https://ncbi.nlm.nih.gov/pubmed/31511356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900254
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