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IL-25 orchestrates activation of Thelper cells via conventional dendritic cells in tissue to exacerbate chronic HDM-induced asthma pathology
House dust mites (HDM) extract is a common trigger of asthma in humans. Chronic exposure to HDM also induces asthma-like pathology in mice. Allergic responses to HDM and other allergens are linked to release of IL-25, IL-33 and TSLP by epithelial cells; these cytokines, especially IL-33, target inna...
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| Pubblicato in: | J Immunol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6783368/ https://ncbi.nlm.nih.gov/pubmed/31511356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900254 |
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