Increased Renal Cellular Senescence in Murine High-fat Diet: Effect of the Senolytic Drug Quercetin

Obesity and dyslipidemia can be associated with cellular senescence, and may impair kidney function. However, whether senescence contributes to renal dysfunction in these conditions remains unclear. Quercetin is an abundant dietary flavonoid that selectively clears senescent cells by inhibiting PI3K...

詳細記述

保存先:
書誌詳細
出版年:Transl Res
主要な著者: Kim, Seo Rin, Jiang, Kai, Ogrodnik, Mikolaj, Chen, Xiaojun, Zhu, Xiang-Yang, Lohmeier, Hannah, Ahmed, Leena, Tang, Hui, Tchkonia, Tamara, Hickson, LaTonya J., Kirkland, James L., Lerman, Lilach O.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783353/
https://ncbi.nlm.nih.gov/pubmed/31356770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2019.07.005
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