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Increased Renal Cellular Senescence in Murine High-fat Diet: Effect of the Senolytic Drug Quercetin
Obesity and dyslipidemia can be associated with cellular senescence, and may impair kidney function. However, whether senescence contributes to renal dysfunction in these conditions remains unclear. Quercetin is an abundant dietary flavonoid that selectively clears senescent cells by inhibiting PI3K...
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| Publicado no: | Transl Res |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6783353/ https://ncbi.nlm.nih.gov/pubmed/31356770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2019.07.005 |
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