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Identification of Genetic Heterogeneity of Alzheimer’s Disease across Age

The risk of APOE for Alzheimer’s Disease (AD) is modified by age. Beyond APOE, the polygenic architecture may also be heterogeneous across age. We aim to investigate age-related genetic heterogeneity of AD and identify genomic loci with differential effects across age. Stratified gene-based genome-w...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Lo, Min-Tzu, Kauppi, Karolina, Fan, Chun-Chieh, Sanyal, Nilotpal, Reas, Emilie T., Sundar, V. S., Lee, Wen-Chung, Desikan, Rahul S., McEvoy, Linda K., Chen, Chi-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783343/
https://ncbi.nlm.nih.gov/pubmed/30979435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2019.02.022
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