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Superiority of combining two independent trials in interim futility analysis
Traditionally, statistical methods for futility analysis are developed based on a single study. To establish a drug’s effectiveness, usually at least two adequate and well-controlled studies need to demonstrate convincing evidence on its own. Therefore, in a standard clinical development program in...
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| Publicado no: | Stat Methods Med Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6783334/ https://ncbi.nlm.nih.gov/pubmed/30957713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280219840383 |
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