p300 Acetyltransferase Is a Cytoplasm‐to‐Nucleus Shuttle for SMAD2/3 and TAZ Nuclear Transport in Transforming Growth Factor β–Stimulated Hepatic Stellate Cells

Nuclear translocation of mothers against decapentaplegic homolog 2/3 (SMAD2/3), core transcription factors of transforming growth factor β (TGF‐β) signaling, is critical for hepatic stellate cell (HSC) differentiation into metastasis‐promoting myofibroblasts. SMAD2/3 have multiple coactivators, incl...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Wang, Yuanguo, Tu, Kangsheng, Liu, Donglian, Guo, Luyang, Chen, Yunru, Li, Qing, Maiers, Jessica L., Liu, Zhikui, Shah, Vijay H., Dou, Changwei, Tschumperlin, Daniel, Voneschen, Luke, Yang, Rendong, Kang, Ningling
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783326/
https://ncbi.nlm.nih.gov/pubmed/31004519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30668
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