Focal Adhesion Kinase Promotes Hepatic Stellate Cell Activation by Regulating Plasma Membrane Localization of TGFβ Receptor 2

Transforming growth factor β (TGFβ) induces hepatic stellate cell (HSC) differentiation into tumor‐promoting myofibroblast, although underlying mechanism remains incompletely understood. Focal adhesion kinase (FAK) is activated in response to TGFβ stimulation, so it transmits TGFβ stimulus to extrac...

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Bibliografische gegevens
Gepubliceerd in:Hepatol Commun
Hoofdauteurs: Chen, Yunru, Li, Qing, Tu, Kangsheng, Wang, Yuanguo, Wang, Xianghu, Liu, Dandan, Chen, Chen, Liu, Donglian, Yang, Rendong, Qiu, Wei, Kang, Ningling
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996408/
https://ncbi.nlm.nih.gov/pubmed/32025610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1452
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