Focal Adhesion Kinase Promotes Hepatic Stellate Cell Activation by Regulating Plasma Membrane Localization of TGFβ Receptor 2

Transforming growth factor β (TGFβ) induces hepatic stellate cell (HSC) differentiation into tumor‐promoting myofibroblast, although underlying mechanism remains incompletely understood. Focal adhesion kinase (FAK) is activated in response to TGFβ stimulation, so it transmits TGFβ stimulus to extrac...

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Bibliographic Details
Published in:Hepatol Commun
Main Authors: Chen, Yunru, Li, Qing, Tu, Kangsheng, Wang, Yuanguo, Wang, Xianghu, Liu, Dandan, Chen, Chen, Liu, Donglian, Yang, Rendong, Qiu, Wei, Kang, Ningling
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996408/
https://ncbi.nlm.nih.gov/pubmed/32025610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1452
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