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Cryo-EM structure of the ClpXP protein degradation machinery

The ClpXP machinery is a two component protease complex performing targeted protein degradation in bacteria and mitochondria. The complex consists of the AAA+ chaperone ClpX and the peptidase ClpP. The hexameric ClpX utilizes the energy of ATP binding and hydrolysis to engage, unfold and translocate...

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Detalles Bibliográficos
Publicado en:Nat Struct Mol Biol
Main Authors: Gatsogiannis, C, Balogh, D, Merino, F, Sieber, SA, Raunser, S
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783313/
https://ncbi.nlm.nih.gov/pubmed/31582852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0304-0
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