Neuropilin-2 contributes to tumorigenicity in a mouse model of Hedgehog pathway medulloblastoma

The Hedgehog (Hh) signaling pathway has been implicated in the most common childhood brain tumor, medulloblastoma (MB). Given the toxicity of post-surgical treatments for MB, continued need exists for new, targeted therapies. Based upon our finding that Neuropilin (Nrp) transmembrane proteins are re...

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Pubblicato in:J Neurooncol
Autori principali: Hayden Gephart, Melanie G., Sophie Su, YouRong, Bandara, Samuel, Tsai, Feng-Chiao, Hong, Jennifer, Conley, Nicholas, Rayburn, Helen, Milenkovic, Ljiljana, Meyer, Tobias, Scott, Matthew P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783276/
https://ncbi.nlm.nih.gov/pubmed/24026530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-013-1216-1
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