Neuropilins are positive regulators of Hedgehog signal transduction

The Hedgehog (Hh) pathway is essential for vertebrate embryogenesis, and excessive Hh target gene activation can cause cancer in humans. Here we show that Neuropilin 1 (Nrp1) and Nrp2, transmembrane proteins with roles in axon guidance and vascular endothelial growth factor (VEGF) signaling, are imp...

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Detaylı Bibliyografya
Asıl Yazarlar: Hillman, R. Tyler, Feng, Brian Y., Ni, Jun, Woo, Wei-Meng, Milenkovic, Ljiljana, Hayden Gephart, Melanie G., Teruel, Mary N., Oro, Anthony E., Chen, James K., Scott, Matthew P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2011
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222900/
https://ncbi.nlm.nih.gov/pubmed/22051878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.173054.111
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