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Na,K-ATPase β(1)-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity

BACKGROUND: The Sonic hedgehog (Shh) signaling pathway plays an important role in cerebellar development, and mutations leading to hyperactive Shh signaling have been associated with certain forms of medulloblastoma, a common form of pediatric brain cancer. While the fundamentals of this pathway are...

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Dettagli Bibliografici
Pubblicato in:Mol Cancer
Autori principali: Lee, Seung Joon, Litan, Alisa, Li, Zhiqin, Graves, Bruce, Lindsey, Stephan, Barwe, Sonali P., Langhans, Sigrid A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544806/
https://ncbi.nlm.nih.gov/pubmed/26286140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0430-1
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