Sonic Hedgehog-Induced Histone Deacetylase Activation Is Required for Cerebellar Granule Precursor Hyperplasia in Medulloblastoma

Medulloblastoma, the most common pediatric brain tumor, is thought to arise from deregulated proliferation of cerebellar granule precursor (CGP) cells. Sonic hedgehog (Shh) is the primary mitogen that regulates proliferation of CGP cells during the early stages of postnatal cerebellum development. A...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee, Seung Joon, Lindsey, Stephan, Graves, Bruce, Yoo, Soonmoon, Olson, James M., Langhans, Sigrid A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739791/
https://ncbi.nlm.nih.gov/pubmed/23951168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071455
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