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Inhibition of epidermal growth factor signaling by the cardiac glycoside ouabain in medulloblastoma
Epidermal growth factor (EGF) signaling regulates cell growth, proliferation, and differentiation. Upon receptor binding, EGF triggers cascades of downstream signaling, including the MAPK and phosphoinositide-3-kinase (PI3K)/Akt signaling pathways. Aberrant expression/activation of EGFR is found in...
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| Publicado no: | Cancer Med |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4302666/ https://ncbi.nlm.nih.gov/pubmed/25052069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.314 |
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