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Inhibition of epidermal growth factor signaling by the cardiac glycoside ouabain in medulloblastoma
Epidermal growth factor (EGF) signaling regulates cell growth, proliferation, and differentiation. Upon receptor binding, EGF triggers cascades of downstream signaling, including the MAPK and phosphoinositide-3-kinase (PI3K)/Akt signaling pathways. Aberrant expression/activation of EGFR is found in...
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| 出版年: | Cancer Med |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Publishing Ltd
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4302666/ https://ncbi.nlm.nih.gov/pubmed/25052069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.314 |
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