Block of an ether-a-go-go-Like K(+) Channel by Imipramine Rescues egl-2 Excitation Defects inCaenorhabditis elegans

K(+) channels are key regulators of cellular excitability. Mutations that activate K(+) channels can lower cellular excitability, whereas those that inhibit K(+) channels may increase excitability. We show that the Caenorhabditis elegansegl-2 gene encodes an eag K(+) channel and that a gain-of-funct...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Weinshenker, David, Wei, Aguan, Salkoff, Lawrence, Thomas, James H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 1999
Pynciau:
ARTICLE
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782970/
https://ncbi.nlm.nih.gov/pubmed/10559392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-22-09831.1999
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